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In addition to reducing liver-related complications, NAFLD management should reduce macrovascular outcomes [27]

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Asia-Pacific Glucagon-like Peptide-1 (GLP-1) Agonists Industry Leaders AstraZeneca Eli Lilly and Company Novo Nordisk A/S Sanofi Aventis Biocon Ltd

Although, there are some of studies related to the treatment of T2DM by berberine in activating this signaling pathway in intestine cell, it is few study about the paracrine effect of GLP-1 in cell ( Conclusion In conclusion, we confirmed in vivo that berberine has the effect of treating T2DM and enhancing the function of islet cell, and then showed that this effect is produced by activating the GLP-1/GLP-1R/PKA signal pathway in the intestine and islet

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