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To view a copy of this licence, visit About this article Cite this article Au, T.Y., Winiewski, O.W., Benjamin, S

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Today 20 , 1836 (2015)

However, the dual activity of KYNA, antagonizing NMDARs and 7nAChRs both of which are critical for normal brain function complicates pharmacological targeting, as achieving therapeutic modulation within an optimal window risks unintended and potentially severe side effects