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Some tumors, such as those dominated by glycolysis, tend to have a poor prognosis, yet they also show greater sensitivity to chemotherapy, whereas glutamate-dependent subtypes are more likely to benefit from immunotherapy [118]

(2018) Low tumor glutathione level as a sensitivity marker for glutamate-cysteine ligase inhibitors, Oncol

This extra phosphate is added by NAD + kinase and removed by NADP + phosphatase

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