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The alternative is the glucagon-like peptide-1 receptor agonist (GLP-1RA)

GLP-1 receptor agonists (often just called "GLP-1s") are injectable or oral medications that mimic a natural hormone your body produces after eating

7 In a 52-week study of 1,995 patients (modified intention-to-treat population) with type 2 diabetes taking up to three oral hypoglycemic agents and at an increased risk of cardiovascular events, tirzepatide was superior to insulin glargine at all three doses

Shed those unwanted pounds and keep them off for good

Before concluding that microdosing is necessary, however, explore all tolerance strategies first

5d), but not in HFD-fed Glp1r KO mice (Fig