Biochemical characteristics of transaldolase deficiency include the accumulation of seven carbon carbohydrates including sedoheptulose, sedoheptulose 7-phosphate, and mannoheptulose as well as open-chain polyols that includes erythritol, arabitol, ribitol, and sedoheptitol
The grid below shows a representative maintenance week at a 2 mg dose from a 10 mg / 5 mg/mL vial (40 units): Because the molecule is long-acting, the exact day is flexible as long as it is consistent the documented protocol keeps a roughly seven-day interval
Of note, the commercial Iscoves Modified Dulbeccos Medium (IMDM) and Serum Free Expansion Medium (SFEM), which were used as the basal medium for erythroblast cultures, contain a supraphysiological concentration of cystine at 292 M as compared to physiological plasma concentration of 4075 M cysteine in SCD patients, which decreased further to 3060 M during vaso-occlusive pain episodes 36
In vitro and ex vivo academic studies show that AHK-Cu helps maintain the lifespan of dermal papilla cells and blocks pathways that lead to premature follicular miniaturization
R.ThomasC
There is no scientific consensus supporting immediate effects
