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Modulators of the p53 pathway, such as FOXO4-DRI and MDM2 inhibitors, selectively eliminate senescent cells but face challenges in clinical translation

Study course: In rats, a procedure of ureter ligation was performed, which led to hydronephrosis, development of fibrosis, damage to tubular cells, and interstitial inflammation

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Keratin-Derived Melanin Analogs : Use hydrolyzed ovine (sheep) keratin claimed to contain melanin fragments