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3e) and an increase in l-carnitine abundance in MYC-overexpressing cells, which was decreased by both inhibition of IDH1 and glutamine starvation (Extended Data Fig

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) He remains cautiously optimistic, however, because the bottom line is that you do see a reduction in cancer incidence with the GLP-1 agonists, he says, and its possible that reduction would be even greater if the researchers had only focused on patients with obesity or overweight

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Much of the spotlight has been on their impressive ability to help people shed significant amounts of weight, but the story doesnt end there