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BMP7 activates brown adipose tissue and reduces diet-induced obesity only at subthermoneutrality

Participants given the highest dose lost around 20 pounds in 12 weeks, and others lost inches from their waist in 6 months

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Generalized tonic-clonic seizure: T1 = 5 minutes

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Methods Animals Animal experiments were performed with adherence to all national and local guidelines and regulations, the Guide for the Care and Use of Laboratory Animals 25 , and the ARRIVE guidelines, and with the approval of the Institutional Animal Care and Use Committee at The University of Texas Medical Branch (UTMB)