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These studies may be complemented by temperature control technologies (e.g., localized heating or the use of temperature-tolerant strains) to better approximate human physiological conditions (Renshaw and Trede, 2012

Driven by leptin and PD-1 signaling, CD8 + T cells shift toward FAO at the expense of glycolysis, decreasing the expression of cytolytic effectors, such as IFN and granzyme B [63]

Inflammation triggers chondrocyte ferroptosis in TMJOA via HIF-1/TFRC

Several widely used tools are available to assess this aspect: the Dermatology Life Quality Index, which evaluates the overall quality of life affected by skin conditions and is known for its ease of use