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Biological Functions Transport of Long-Chain Fatty Acids Into the Mitochondrial Matrix The essential function of carnitine is to transport LCFAs from the cytoplasm to the mitochondrial matrix for subsequent degradation by -oxidation, known as carnitine shuttle (29)

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After a one-month break, healthcare providers typically recommend restarting at a lower doseoften 2.5 mg weeklythen gradually re-escalating to minimize gastrointestinal side effects while restoring metabolic benefits

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