But "improvement" in this context means TSH levels changed, and that can go in either direction depending on your current dose
When semaglutide and lifestyle interventions were discontinued on the individuals from the STEP 1 trial, they regained the majority of their weight lost
CMS has said it will release more detail on how the two programs interact during the 2027 demonstration period
Trial population differences matter significantly
When You Might Use the Shorter (2-Month) Timeline Your doctor might recommend the manufacturer-suggested 2-month washout if youre over 37 and age-related fertility decline is a pressing concern, your GLP-1 use was brief (only 8-12 weeks or less), youre taking liraglutide with its shorter half-life meaning faster clearance, your cycles regulated quickly and youre having regular ovulatory cycles by 6-8 weeks post-medication, or other individual factors in your case warrant it
Setting the Scene: Why the Injectable Era Had a Ceiling The anti-obesity treatment market has become synonymous with one of the most closely watched rivalries in modern pharmaceuticals: Novo Nordisk versus Eli Lilly