Millions of people are now losing significant weight using GLP-1 medications
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This may be due to the fact that bile acids entering the intestine stimulate intestinal secretion and expression of the gut-derived hormone FGF19 via bile acid-FXR signaling (Mulla et al., 2019), which stimulates hepatic glycogen synthesis in an insulin non-dependent manner, restrains hepatic gluconeogenesis, and exerts hypoglycemic effects
Systematic review: the epidemiology of the hepatobiliary manifestations in patients with inflammatory bowel disease
Lo que empez como un goteo de ancdotas en las consultas de los mdicos ha acabado siendo objetivo de estudio por diferentes equipos de investigacin que han visto aqu una nueva forma de entender el mecanismo de las adicciones en los humanos