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Retatrutide once weekly for the treatment of obesity

That makes it mechanistically independent of appetite or metabolic rate, which is the basis for the article's argument that the two drugs target different pathways

Buse JB, Rosenstock J, Sesti G et al (2009) Liraglutide once a day versus exenatide twice a day for type 2 diabetes: a 26-week randomised, parallel-group, multinational, open-label trial (LEAD-6)

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