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The decision depends on individual goals, tolerance, and how much additional weight loss justifies the additional side effect burden

Shaking also creates foam, which dramatically increases the surface area exposed to air and can physically denature proteins and larger peptides through the mechanical forces at bubble interfaces

But pH is only one factor and water of all pH levels is corrosive in varying degrees

Conversely, Ding et al

It may have been reviewed by a licensed physician, but is not intended to serve as a substitute for professional medical advice

Informed consent Written informed consent was obtained from the patients and/or their families