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Typical criteria include: Documented diagnosis of type 2 diabetes with inadequate glycemic control on metformin or other first-line agents BMI 27 kg/m with weight-related comorbidity or BMI 30 kg/m (for weight management indications) Trial and failure of alternative therapies Absence of contraindications Coverage for weight management indications under commercial plans has expanded but remains inconsistent, with many employers specifically excluding obesity medications from pharmacy benefits

doi:10.1038/34657

Those with previous allergic reactions to other GLP-1 receptor agonists, multiple drug allergies, or a history of anaphylaxis to any substance require careful assessment and thorough education about recognizing allergic symptoms

Metabolic labs: Fasting glucose, HbA1c, lipid panel, liver enzymes (ALT, AST)

What we want is money back for the people that paid for snake oil, Chimicles said

immunological system