This common concern deserves a clear, evidence-based answer
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In 2002, the International Continence Society proposed changing the name from IC to IC/PBS and defined the condition as the complaint of suprapubic pain related to bladder filling, accompanied by other symptoms such as increased daytime and night time frequency, in the absence of a proven urinary infection and other obvious pathology. 2 IC/PBS has been associated with other chronic pain syndromes, such as fibromyalgia, irritable bowel syndrome, and chronic fatigue syndrome
[17] Elias MF, Brown CJ
The most common injuries include gastroparesis (stomach paralysis), intestinal blockage (ileus), gallbladder disease requiring surgery, vision loss (NAION), pancreatitis, and kidney damage
Once reconstituted with bacteriostatic water, store in the refrigerator at 2-8 degrees Celsius and use within 4-6 weeks