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[21] In addition, diuretics reduce the risk of stroke and cardiovascular disease in patients with diabetes

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however, because this was a retrospective target trial emulation with a relatively small number of events, it is not yet practice-changing and should instead be viewed as a signal that supports further research into the role of GLP-1 receptor agonists in epileptogenesis. Limitations and future directions The authors emphasised that the study design was observational, despite using advanced statistical methods to emulate a clinical trial