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Using a mouse model, we identified the key factor through which NRTP damages ovaries and then designed targeted therapies to protect ovaries in a mouse model, thereby providing novel strategies for the future clinical application of targeted protection of ovaries from NRTP-induced damage

As further support, we determined the expression levels of TSS pathway factors in spleen erythroblasts of SCD mice under chronic DMF treatment

Commercially available TaqMan Gene Expression Assays (RUNX-2 Hs00231692_m1

Global IGF-1 KO mice have age-related vision loss

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