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Hormonal alterations, including reduced gonadal, thyroidal, and somatotropic activity, further impair bone formation and promote catabolism of lean tissues, including bone

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8df) revealed that in the M group, the percentage of M1 macrophages significantly increased (34.97% in the M group and 27.75% in the CTR group), and the percentage of M2 macrophages significantly decreased (25.68% in the M group and 29.82% in the CTR group)

When NMDAR activity is excessive, neurons allow more calcium influx, which can increase excitatory stress, mental rigidity, sensory overload, and intrusive thought intensity