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We show in mice with cartilage autoantibody-induced arthritis that early immune activation and a cytokine storm were mainly driven by vascular cells and monocytes/macrophages in the dorsal root ganglion

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They will also exclude other contributing factors such as concurrent medications, hypothyroidism, or structural bowel abnormalities

Effects of prednisolone on serum and tissue fluid IGF-I receptor activation and post-receptor signaling in humans

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Over-the-counter alternatives like orlistat delivered only 23% incremental weight loss in 2024 meta-analyses, reinforcing prescriber reliance on higher-efficacy options