diabetes management algorithm step 2 medicine shelf glyburide semaglutide 🔴 Holistic Treatment of Diabetes: 2025 ADA Standards of Care ▪️ Cardiovascular risk: Use GLP-1 RA or SGLT2 inhibitors for glycemic control & cardiovascular risk reduction. ▪️ Heart failure: SGLT2 inhibitors recommended NICE type 2 diabetes management

The theoretical advantage is that the GLP-1 agonist manages caloric intake while the GH secretagogue preserves lean mass and enhances lipolysis

Patients with a history of pancreatitis, particularly those with chronic pancreatitis or recurrent acute episodes, may be at increased risk for pancreatitis exacerbation

If youre curious about trying an oral option after using an injectable, talk with your provider

Inflammation of blood vessels (vasculitis) can cause fragile vessels and skin changes, leading to bruising or purpura

Whether BRP will match semaglutide efficacy in humans remains unknown until clinical trials complete

This guidance should not be used as a substitute to reading the patient information leaflet or having a conversation with a healthcare professional as part of the prescribing process.