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Other neuronal systems are also affected, resulting in non-motor symptoms including cognitive decline

406 FGF21 is recognized as a stress response factor that addresses mitochondrial dysfunction in cells

Moreover, nuclearmitochondrial genome interactions differ by sex, influencing longevity and stress adaptation, with females exhibiting more robust mitochondrial maintenanceagain, largely attributed to estrogenic signaling (Tower, 2015)

Activation of the GLP-1 receptor signalling pathway: A relevant strategy to repair a deficient beta-cell mass

von Wussow, U., Klaus, J

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