coming off of glp 1 Trajectory weight regain after cessation of GLP-1 receptor agonists: a systematic review and nonlinear meta-regression Weight loss maintenance after discontinuing

Cancers Cancer cells are susceptible to perturbation of thiol metabolism, where excessive iron release and subsequent lipid peroxidation contribute to carcinogenesis [224]

The bulk of evidence is pre-clinical, concentrated in skin, wound-healing, and hair-follicle research

These findings suggest that certain cytokines might exert positive or negative effects on different tissues, suggesting that tissue-specific targeted therapy is an essential strategy to protect other normal tissues, such as the ovary, from NRTP-induced damage

Early-life gut microbiota imbalances may predispose individuals to PTSD susceptibility after trauma exposure (Leclercq et al., 2016)

The mTOR pathway regulates cell growth and metabolism, and inhibiting it mimics the effects of caloric restriction, which has been linked to longevity

Oncol Rep 33(6):30613068 Almalki RS, Gazzaz M, Miski SF, Fayed HM, Mohamed B, Hessin AF et al (2025) Repositioning gemigliptin for the alleviation of thioacetamide-induced liver fibrosis in rats: Targeting TLR4/MAPK, SIRT1/AMPK/Nrf2, PI3K/AKT/mTOR axis and apoptosis