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GGT catalyzes the transfer of a glutamyl residue (linked through glutamate gamma carboxylic acid to an amine or to another amino acid) to an acceptor, 102 thereby maintaining adequate levels of glutathione

Glutathione has a reputation problem: it's one of the most talked-about antioxidants out there, but standard oral forms are notoriously hard for the body to absorb

Similarly, deletion of the Ca 2+ sensor STIM1 leads to spontaneous activation of the STING-TBK1-IRF3 pathway, which results in type I IFN-mediated ER stress (130)

Dermatological Reviews, 7(2), e70067

2024 Mar 30;13(4):425