Chronic inflammation in the digestive tract increases the risk of perforations or the formation of abscesses, both of which may require surgical intervention
In summary, semaglutide offers a promising new approach to managing asthma, particularly for patients who are obese or have difficult-to-control asthma
Between 2024 and 2025, 13 major deals valued at $13.6 billion focused on multi-target regimens combining GLP-1s with agents such as amylin, myostatin, or calcitonin analogs
The compound also appears to reduce hepatic steatosis (fatty liver) by enhancing hepatic fatty acid oxidation and reducing lipogenesis
Prophylactic probiotic supplementation for preterm neonatesA systematic review and meta-analysis of nonrandomized studies
A 2024 study published in Nature Scientific Reports surveying over 162,000 patients over an eight-year period reported a significant association of psychiatric symptoms in patients taking GLP-1 RAs, including a 195% risk of depression, 108% risk of anxiety, and 106% increased risk for suicidal behavior