Consequences of a deficiency: A deficiency can lead to increased oxidative stress, persistent fatigue, reduced performance and a higher susceptibility to infections
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Other genes, although with ARE motifs, present CpG islands in their proximal promoters such as GCLC and GCLM, which are characterized by significant association of active histone codes such as H3K4Me1-3, H3K9Ac, H3K27Ac, and H3K79Me2, suggesting a regulatory role of CpG islands in chromatin modifications
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Refer to the cited studies in the Research Studies section above for original source data
Scientists use the ratio between these forms to measure cell redox status