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These data reflect exposure of 1,071 patients to RYBELSUS with a mean duration of exposure of 41.8 weeks

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doi: 10.1073/pnas.1603244113 198 LiCDongXDuWShiXChenKZhangWet al

Upon binding with specific death ligands, death receptors receive extracellular death signals and initiate apoptotic signaling by recruiting specific adaptor proteins, which subsequently activate the caspase cascade