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PloS One, 8(6), e66418

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Bio/Physico-chemical Assay Bio/Physico-chemical Assay Flow Cytometry Cell Proliferation/Viability Assay Flow Cytometry Biological Activity In Vitro The sequence of Glucagon-Like Peptide after residue 7 shows similarities to glucagon and to other biologically active members of the secretin peptide family, particularly glucose-dependent insulinotropic peptide (GIP)

271 ci-Ins2 silencing in pancreatic islets leads to decreased expression of several genes important for insulin secretion ( Rapgef4 , Pld1 , Pclo , and Cacna1c ) by interacting with the TAR DNA-binding protein 43 (TDP43), thereby contributing to -cell dysfunction during diabetes

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The researchers wanted to further underline the important role of GLP-1