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(CACT) - CoA

Identification of extremely reactive gamma-ketoaldehydes (isolevuglandins) as products of the isoprostane pathway and characterization of their lysyl protein adducts

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After blocking, membranes were incubated with primary and fluorescent-conjugated secondary antibodies for 1 h at room temperature with four 10-min washes with fresh 0.1% PBS-Triton X-100 after both the primary and secondary antibody incubations

Confirmed in isolated aortic tissue (Hsieh et al., 2020)

Like Ozempic, it has been approved for blood sugar management in Type 2 diabetes