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GLP-1 medications address the underlying pathology by improving beta-cell function and reducing hepatic glucose production

Work with your doctor to create a Letter of Medical Necessity

1 Eating enough fiber and drinking plenty of fluids each day can help keep your digestive system moving

Tirzepatide (Zepbound): In the SUMO 4 trial, people taking the highest dose of tirzepatide lost an average of 21.4% of their body weight over 72 weeks

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In renal impairment, this axis contributes to a feedback loop driven by gut dysbiosis, systemic inflammation, oxidative stress, blood pressure dysregulations, and neurocognitive decline (Bugnicourt et al., 2013