muciniphila secretes a protein called P9 that has been shown to upregulate the expression of glucagon-like peptide-1 (GLP-1), an incretin hormone secreted by the intestinal L-cells ( GLP-1 is known as an insulinotropic hormone, because it induces the release of insulin from pancreatic -cells in response to rising serum glucose levels ( -cells, treatment with GLP-1 induced mitochondrial biogenesis, through a mechanism that involved increased cAMP activation
There has been no evidence of increased pancreatic disease in the large cardiovascular outcome trials studying the safety of GLP-1 receptor agonists
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In terms of body weight, plasma glucose and cholesterol concentrations, no significant differences, were observed between the two groups (Table 1)
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3c), suggesting the successful formation of the inorganicorganic hybrid structure