Freezing damages the peptide structure irreversibly
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Dina Hirsch, Northwell Healths clinical director of bariatric psychology and behavioral weight management, said in an email GLP-1 drugs, which work to reduce weight in part by quieting repetitive thoughts about eating, may have "neuroprotective and anti-inflammatory effects" that make them effective treatments for depression
In phentermine and topiramate extended-release clinical trials, the peak reduction in serum bicarbonate typically occurred within 4 weeks of titration to the assigned dose, and in most patients, there was a correction of bicarbonate by week 56, without any dosage reduction
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Repeated freeze-thaw cycles should be avoided, as they can degrade the peptide and reduce potency