heart disease, such as coronary heart disease and hypertension
The SUSTAIN trial series and SURMOUNT trials tracked vision-related complaints, though serious ophthalmologic events were uncommon across all groups
Weeks 1 through 4: the adjustment phase Gastrointestinal side effects peak during the first month and with each subsequent dose increase
The mechanisms underlying weight regain are multifactorial and include metabolic adaptation with decreased energy expenditure, hormonal changes affecting appetite regulation, anatomical alterations such as gastric pouch or stoma dilation, and psychosocial factors including maladaptive eating behaviors
A consistent morning system (same time, same steps) helps prevent missed doses and improves results over time
For investors, this case sits alongside broader product and pipeline developments in obesity and hemophilia