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Whereas IRP1 with coordinated FeS cluster functions as aconitase, iron deficiency activates the mRNA binding activity of IRP1

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J Pharm Biomed Anal 114, 113120 (2015)

Although current guidelines (ESH and ACC/AHA) recommend the measurement of arterial stiffness for personalized risk stratification of patients with hypertension, a better understanding of its pathophysiology is needed to define new targets for prevention and to bring us closer to healthy vascular aging

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