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The Zepbound (tirzepatide) label recommends switching to a non-oral birth control method, or adding a barrier method, for 4 weeks after starting Zepbound and for 4 weeks after each dose increase

Once the FDA declared the shortage resolved, 503A pharmacies were ordered to stop dispensing compounded tirzepatide by February 18, 2025 , followed by 503B facilities on March 19, 2025

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A significant dose-dependent decrease in body weight from 7.5 to 12.9 kg was observed in the tirzepatide group, compared to a 2.3 kg increase in the insulin degludec group

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We dive into what this means for those at risk or being treated for this cancer