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2.1 Oxidative stress in schizophrenia SZ is a severe mental disorder affecting approximately 0.3 to 0.66% of the population, significantly impairing quality of life and imposing a substantial socio-economic burden (Maas et al., 2017)

Combining genetic context with clinical biomarkerssuch as fasting insulin, HbA1c, and baseline weight statusallows providers to personalize tirzepatide dosing and escalation schedules

Close monitoring is recommended to avoid toxicity

This alters EC properties through the production of a broad spectrum of proteases and coagulation factors, which disrupt NVU cells and contribute to BBB dysfunction, leading to prolonged inflammation [211, 213,214,215]

GLP-1 receptor agonists: targeting both hyperglycaemia and disease processes in diabetes

How does PlexusDx semaglutide compare to Wegovy for long-term use