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If the intestinal barrier is breached, uremic substances, including indole sulfate, para-cresol sulfate, and trimethylamine N-oxide (TMAO), can lead to endotoxemia and systemic inflammation (156, 157)

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It also important for optimal brain function.89 Inositol deficiency may manifest as symptoms of constipation, high cholesterol, vision problems, and hair loss

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This is sort of the popularized version of it