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Mol Endocrinol (2003) 17(12):2393403

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The standard titration schedule moves from 0.25 mg to 0.5 mg, then 1 mg, and finally 2.4 mg as the maximum therapeutic dose for weight loss

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Lincoff AM, Brown-Frandsen K, Colhoun HM, Deanfield J, Emerson SS, Esbjerg S, Hardt-Lindberg S, Hovingh GK, Kahn SE, Kushner RF, et al: Semaglutide and Cardiovascular Outcomes in Obesity without Diabetes