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Individuals with active malignancy, uncontrolled serious illness, pregnancy, breastfeeding, or complex immune or coagulation disorders are commonly considered poor candidates and require alternative strategies

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Therefore, the two substances are unlikely to interfere with each other's absorption, distribution, metabolism, or excretion

Inflammasomes promote the maturation and secretion of the cytokine precursors pro-IL-1 and pro-IL-18 in the process of innate immune defense by inducing the activation of caspase-1, thereby triggering an inflammatory response

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Urology 2009