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The latter type also targets glucose-dependent insulinotropic polypeptide (GIP) receptors, as well as GLP-1 receptors, for a stronger effect

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10.1515/jbcpp-2014-0128 J

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Yes variants in GLP1R, GIPR, FTO, MC4R, and TCF7L2 are associated with differential GLP-1 response

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doi: 10.3109/0886022X.2012.723777

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No single mechanism has been confirmed, but several possible explanations exist

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