Therefore, the authors concluded that, at least in their studied group, DPP4 gene polymorphisms seem to be unrelated to the inter-individual risk of developing obesity-related metabolic complications ( In another study, visceral adipose tissue DNA of 92 severely obese, non-diabetic female patients was analyzed for methylation rate in the DPP4-promoter CpG island and compared between different DPP4 polymorphisms
Scrocchi LA, Brown TJ, MaClusky N et al (1996) Glucose intolerance but normal satiety in mice with a null mutation in the glucagon-like peptide 1 receptor gene
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