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2 large, long-term trials (GEM, GuidAge) found no dementia-prevention effect in healthy older adults

Pharmacologic analogues of GLP-1 were first approved for type 2 diabetes (T2D) in the mid-2000s (e.g

[DOI] [PubMed] [Google Scholar] 112.Meng J, Ma X, Wang N, Jia M, Bi L, Wang Y, et al

The two most widely known GLP-1 treatments today are: Semaglutide (Wegovy, Ozempic) A once-weekly injection proven to decrease appetite, reduce cravings, and promote consistent weight loss

[DOI] [PubMed] [Google Scholar] 47.Marconi S., Castiglione G., Turano E., Bissolotti G., Angiari S., Farinazzo A.Bonetti B