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Surgical recovery often depletes the bodys glutathione reserves due to oxidative stress caused by surgery, anaesthesia, and medications

The authors conclude that the renal benefits cannot solely be explained by weight reduction or risk factor reduction, although these may contribute, and the mechanisms of kidney protection are likely to be multifactorial and may include decreased oxidative stress, inflammation and fibrosis in the kidney

coli GspS have been applied for mammalian cells to convert GSH to biotin-glutathionylspermidine (biotin-Gsp) which subsequently modified proteins by Biotin-Gsp- S -thiolation (Chiang et al., 2015)

Prognostic value of malondialdehyde serum levels in severe sepsis: a multicenter study