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The efficacy of antidepressant drugs has been questioned since the first meta-analyses of the late 1990s [16]

Examining adult brains for metabolites that may lend to the etiology of a group of disorders known to form in utero does not necessarily provide a causal framework for the disorder

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Elismetrep is the only TRPM8 antagonist being studied for the acute treatment of migraine, and after delivering a favorable clinical profile through its novel mechanism, it shows potential as a new therapeutic option for patients who are suffering from migraine