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Pharmacological modulation of cholesterol 7-hydroxylase (CYP7A1) as a therapeutic strategy for hypercholesterolemia

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The best-fit patients for GLP-1 RAs are those with ASCVD with a high risk of future stroke (e.g., with history of stroke or revascularization, or with evidence of significant artery narrowing)

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Results We revealed that intracellular BPC157 engages the E3 ubiquitin ligase adaptor protein FBXO22 through its proline residue at position 3

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