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PMID: 36588283

Aromatic amino acids, including phenylalanine and tryptophan, and aliphatic amino acids are the most efficient agonists of CaSR

[231] when triggered by amphetamine, this pathway activates Ras homolog A (RhoA) and its downstream protein kinase, Rho-associated coiled-coil kinase (ROCK), an effect that internalizes both DAT and the neuronal glutamate transporter EAAT3

doi: 10.1007/s40471-020-00236-3 2

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And while brain research into GLP-1 and reward circuits is still in its early days, its a field to watch closely