This seemingly small chemical modification brings profound functional changes: the acetylated thiol group is protected from oxidation and enzymatic breakdown, while the overall molecules lipophilicity is significantly enhanced, allowing it to cross biological membranes more easily
This is detailed further below
While vitamin C seems to get all the accolades for immunity, Glutathione is the under-recognized supporting actor who deserves the starring role
Clinical Toxicology, 59, 1196 - 1227
On top of that, it can also reduce the expression of pro-inflammatory cytokines, enhance antioxidant defenses via glutathione, and potentially reduce the production of reactive oxygen species (free radicals) (2-4)
Sadowska-Przytocka A, Gruszczyska M, Ostaowska A, Antosik P, Czarnecka-Operacz M, Adamski Z, cka K