Glutathione Side Effects on Skin and Hair The use of glutathione for skin and hair benefits should be approached with caution, as side effects may occur: Skin Discoloration : Excessive use of glutathione for skin lightening can lead to uneven skin tone, with some areas becoming lighter than others
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GSH is naturally produced in the liver and under ideal circumstances, does an excellent job of alleviating free radical damage and oxidative stress
Due to its well-characterised molecular structure, reproducible analytical profile and broad scientific relevance, glutathione remains an important research material for biochemical, molecular and cellular investigations
10.1089/ars.2014.5863 17 CostanzoG.BuccheriR.CosentinoG.RealeC.ZuccalS.MarrazzoA.et al (2025)
When ingested orally, glutamine is partially hydrolyzed in the gastrointestinal tract, which leads to substantial inactivation of the compound