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What the Clinical Data Actually Shows The most definitive comparison comes from the SURMOUNT-5 trial, a direct head-to-head study published in the New England Journal of Medicine comparing tirzepatide 10 mg and 15 mg against semaglutide 2.4 mg in adults with obesity but without diabetes

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In a recent online survey, N = 600 patients with T2D were asked to provide their treatment preferences regarding a once-daily oral GLP-1RA compared with a once-weekly injectable GLP-1RA

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Eat smaller, more frequent meals Regular smaller meals and snacks can help reduce the risk of blood sugar dips, especially if your appetite is reduced while taking Wegovy

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