They benefit people who have mild B12 shortages, feel tired because of a poor diet, or need daily nutritional help
In practice, clinicians may consider it for weight management support in adults with overweight or obesity, particularly when lifestyle measures alone have not been sufficient
As with any injection, mild side effects can occur, and rare allergic reactions are possible
Structural and regulatory signaling processes
Phase 2 clinical trial data published in the New England Journal of Medicine (Jastreboff et al., 2023) demonstrated mean body weight reductions of up to approximately 24% over 48 weeks in adults with obesity a notable finding, though long-term durability data and head-to-head comparisons with other treatments are not yet available
Some benefits, like improved skin radiance and sustained energy, build over time with consistent treatments